MECABIONIC seminars series: Atef Asnacios (Université Paris Cité)
Science and society
Published on June 25, 2024–Updated on June 25, 2024
Dates
on the July 2, 2024
11h
Location
Institut de Physique de Nice
Salle de conférences
Mechanobiology at the single cell level
Mecabionic seminars series
Abstract:
Cells are under the control of genetic programs. However, over the last decades, many investigations have been dedicated to the role of physical and mechanical cues in biological functions, leading to the emergence of mechanobiology. In this context, as a physicist and an experimentalist, I will review some technical developments in single cell rheometry and force measurement that allowed us to reveal the physics behind various biological functions. I will present examples from both animals and plants. For instance, I will discuss a parallel between rigidity sensing by animal cell and impedance matching, will show how mechanical features of antigen presenting cells are modulated by inflammation and stimulate the immune response, and will present some aspects of adaptation of plant growth to stiffening of the soil.
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